About The Condition
Lines around the mouth are one of the most commonly treated cosmetic concerns, and for good reason: the mouth is central to facial expression, communication, and overall appearance. These lines fall into two main categories. Perioral lines, sometimes called smoker’s lines or lip lines, are fine vertical creases that form in the skin directly above and below the lips. Nasolabial folds, on the other hand, are the deeper creases running from the sides of the nose down toward the corners of the mouth. These lines affect just about everyone.
The primary reason for these lines is the gradual loss of collagen, elastin, and hyaluronic acid that occurs naturally with age. As these proteins diminish, the skin becomes thinner and less resilient, making it easier for repeated movements to leave a lasting impression. Repetitive facial movements also contribute to crease formation over decades of use. Genetics, smoking, and significant weight fluctuations can compound these effects, causing lines to appear earlier or deepen more quickly in some individuals.
Beyond the physical changes, the emotional impact is real and valid. The mouth is inseparable from how we express joy, warmth, and connection. When lines and folds become a source of self-consciousness, many people begin avoiding photographs, feel hesitant in social or professional settings, or find themselves preoccupied with their appearance in ways that were never an issue before.
Our Providers
Meet The Team
Our founding team is composed of dermatology expert providers and managers that have been active participants in the dermatology and aesthetic medical industry for over 20 years each.
Treatment Options
The good news is that lines around the mouth are among the most treatable concerns in aesthetic medicine. At SkinPerfected, we take a comprehensive approach, combining injectables, energy-based devices, microneedling, and medical-grade skincare to address both the visible lines and the underlying structural changes that cause them.
Juvederm
What Is It?
Juvederm is a family of FDA-approved hyaluronic acid (HA) dermal fillers formulated specifically for different areas and concerns of the face. For lines around the mouth, products such as Juvederm Ultra XC. Juvederm Vollure and Juvederm Volbella XC are commonly used to restore lost volume in the nasolabial folds, refine the lip border, and soften vertical perioral lines.
Key Benefits
Juvederm delivers immediate, visible softening of nasolabial folds and perioral lines, with results that feel natural and integrate smoothly with surrounding tissue. Downtime is minimal, with most patients returning to their normal routine the same day, and the filler continues to stimulate the skin’s own collagen production in the weeks following treatment.
Candidacy
Juvederm is well-suited for adults who have noticeable nasolabial folds, volume loss around the mouth, or lip border definition that has softened with age. It is also an excellent option for those seeking an immediate result without surgery or extended recovery. Candidates should be in generally good health, not pregnant or breastfeeding, and should not have active skin infections or cold sores in the treatment area.
SkinPen and Regenerative Microneedling
What Is It?
At SkinPerfected, we take microneedling beyond the standard with Regenerative Microneedling, a more advanced approach that pairs SkinPen, the first FDA-cleared microneedling device, with PDGF (platelet-derived growth factor). SkinPen creates thousands of controlled micro-channels in the skin using sterile needles, triggering the body’s natural wound-healing response. When PDGF is infused alongside this process, it supercharges that response, delivering targeted growth factors directly into the skin to accelerate cellular repair, collagen production, and tissue regeneration at a deeper level than microneedling alone can achieve.
Key Benefits
Regenerative Microneedling with PDGF stimulates the skin’s own collagen and elastin from within, gradually firming and refining the perioral area in a way that looks entirely natural. Around the mouth, this is particularly effective for softening the crepey quality above the upper lip, improving skin texture and tone, and reducing fine line depth over a series of treatments. The addition of PDGF amplifies the results of the microneedling, supporting faster tissue remodeling and a more robust regenerative response. Because the treatment does not rely on heat or light energy, it is also safe for all skin tones with minimal risk of post-inflammatory hyperpigmentation.
Candidacy
Regenerative Microneedling with PDGF is an excellent choice for patients who want to improve overall skin quality and gradually soften fine perioral lines without injectables. It is especially well-suited for those whose primary concerns are skin texture, laxity, or early lines rather than deep folds requiring volumetric correction. It is suitable for all skin types and tones, and is a particularly strong option for patients looking for a biologically driven, growth-factor-enhanced approach to skin renewal and lines around the mouth.
SkinPerfected Renewal
What Is It?
SkinPerfected Renewal is a signature combination treatment pairing BBL HEROic and HALO Tribrid to correct, renew, and transform the skin in a single customized session. BBL HEROic uses broadband light energy to target pigmentation, sun damage, redness, and uneven tone, while HALO Tribrid delivers fractional laser resurfacing to refine texture, stimulate collagen, and soften fine lines. Around the mouth, this dual approach is particularly effective for improving skin tone, smoothing crepiness above the upper lip, and restoring a brighter, more youthful appearance to the entire perioral area.
Key Benefits
Because SkinPerfected Renewal combines corrective and collagen-stimulating technologies in one treatment, it addresses both surface-level concerns and deeper structural changes in the skin simultaneously. Patients can expect a brighter tone, smoother texture, minimized pores, and a lit-from-within glow, with results that continue to develop over the weeks following treatment as collagen remodeling progresses. It is both corrective and confidence-boosting, delivering next-level rejuvenation that would otherwise require multiple separate treatments.
Candidacy
SkinPerfected Renewal is ideal for patients who want meaningful, visible improvement in skin quality around the mouth rather than subtle maintenance alone. It works well for those experiencing fine lines, uneven tone, sun damage, dullness, and mild to moderate texture concerns. Because the treatment involves both light and laser energy, patients with active tans, those who are highly photosensitive, or those taking photosensitizing medications may need to wait or adjust their plan before moving forward.
Medical Grade Skincare: Featuring: Alastin, AlumierMD, and Plated
What Is It?
No treatment plan for lines around the mouth is complete without a targeted at-home skincare regimen using pharmaceutical-grade formulations. Medical-grade skincare differs from over-the-counter products in that the active ingredients are present in clinical concentrations and are formulated to penetrate beyond the surface of the skin, where they can make a meaningful difference. At SkinPerfected, we curate products from trusted brands, each bringing distinct technology and unique benefits to perioral rejuvenation.
Key Benefits
Medical-grade skincare delivers real, measurable change in the skin rather than surface-level results. A well-designed regimen protects and extends the results of in-office procedures, addressing the root causes of perioral aging, including collagen loss, at home between appointments. Regimens are fully customizable to your skin type, concerns, and treatment plan, and products like Plated provide regenerative support that works with the energy-based and injectable treatments we offer.
Candidacy
Medical-grade skincare is appropriate for virtually every patient. For those in the early stages of perioral aging, a targeted regimen may be all that is needed to slow the progression of lines and maintain skin quality for years. For patients undergoing in-office treatments, these products serve as an essential complement to protect the investment made in the treatment room and keep results lasting longer.
Book A Consultation
Lines around the mouth are one of the most treatable concerns in aesthetic medicine, and you do not have to navigate the options alone. At SkinPerfected, every treatment journey begins with a thorough, unhurried consultation where your provider takes the time to understand not just what you see in the mirror, but what you want to feel when you look there. There is no one-size-fits-all answer, and we would never treat you like there is.
Whether you are exploring injectables for the first time, looking to build on treatments you have had elsewhere, or simply want expert guidance on where to start, we are here to help you move forward with clarity and confidence. Book your consultation with SkinPerfected today and take the first step toward skin that looks as good as you feel.